Evaluation of Serum Cryptococcal Antigen Testing Using Two Novel Semiquantitative Lateral Flow Assays in Persons with Cryptococcal Antigenemia
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چکیده
منابع مشابه
Evaluation of Fingerstick Cryptococcal Antigen Lateral Flow Assay in HIV-Infected Persons: A Diagnostic Accuracy Study
BACKGROUND Cryptococcus neoformans is the most common cause of adult meningitis in sub-Saharan Africa. The cryptococcal antigen (CRAG) lateral flow assay (LFA) has simplified diagnosis as a point-of-care test approved for serum or cerebrospinal fluid (CSF). We evaluated the accuracy of the CRAG LFA using fingerstick whole blood compared with serum/plasma and CSF for diagnosing meningitis. MET...
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1791. Evaluating Cryptococcal Antigen Lateral Flow Assay by Fingerstick Whole Blood in HIV-Infected Persons with Meningitis Darlisha Williams, MPH; Kiiza Tadeo,; Sruti Velamakkani,; Reuben Kiggundu,; David Meya, MMed; Joshua Rhein, MD; David Boulware, MD, MPH; Center for Infectious Diseases & Microbiology Translational Research, University of Minnesota, Minneapolis, MN; Infectious Disease Insti...
متن کاملPreheating of urine improves the specificity of urinary cryptococcal antigen testing using the lateral flow assay
1 National Institute of Infectious Diseases Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro, Brazil, 2 Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil, 3 Centre for Infectious Diseases and Microbiology, Sydney Medical School-Westmead Hospital, Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Westmead Institute for Medical Research, Sydney, New Sout...
متن کاملPrevalence of Cryptococcal Antigenemia and Cost-Effectiveness of a Cryptococcal Antigen Screening Program – Vietnam
BACKGROUND An estimated 120,000 HIV-associated cryptococcal meningitis (CM) cases occur each year in South and Southeast Asia; early treatment may improve outcomes. The World Health Organization (WHO) recently recommended screening HIV-infected adults with CD4<100 cells/mm(3) for serum cryptococcal antigen (CrAg), a marker of early cryptococcal infection, in areas of high CrAg prevalence. We ev...
متن کاملPerformance of Cryptococcal Antigen Lateral Flow Assay Using Saliva in Ugandans with CD4 <100
BACKGROUND Cryptococcal meningitis can best be diagnosed by cerebrospinal fluid India ink microscopy, cryptococcal antigen detection, or culture. These require invasive lumbar punctures. The utility of cryptococcal antigen detection in saliva is unknown. We evaluated the diagnostic performance of the point-of-care cryptococcal antigen lateral flow assay (CrAg LFA) in saliva. METHODS We screen...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2020
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.02046-19